Iftar in Japan
Ramadhan in Korea
Thursday, May 31, 2018
Wednesday, May 30, 2018
Poem: Sympathy
Sympathy
I know what the caged bird feels, alas!
When the sun is bright on the upland slopes;
When the wind stirs soft through the springing grass,
And the river flows like a stream of glass;
When the first bird sings and the first bud opes,
And the faint perfume from its chalice steals—
I know what the caged bird feels!
I know why the caged bird beats his wing
Till its blood is red on the cruel bars;
For he must fly back to his perch and cling
When he fain would be on the bough a-swing;
And a pain still throbs in the old, old scars
And they pulse again with a keener sting—
I know why he beats his wing!
I know why the caged bird sings, ah me,
When his wing is bruised and his bosom sore,—
When he beats his bars and he would be free;
It is not a carol of joy or glee,
But a prayer that he sends from his heart’s deep core,
But a plea, that upward to Heaven he flings—
I know why the caged bird sings!
Tuesday, May 29, 2018
Poem - I Know Why The Caged Bird Sings
I Know Why The Caged Bird Sings - Maya Angelou
The free bird leaps
on the back of the wind
and floats downstream
till the current ends
and dips his wings
in the orange sun rays
and dares to claim the sky.
But a bird that stalks
down his narrow cage
can seldom see through
his bars of rage
his wings are clipped and
his feet are tied
so he opens his throat to sing.
The caged bird sings
with fearful trill
of the things unknown
but longed for still
and his tune is heard
on the distant hill for the caged bird
sings of freedom
The free bird thinks of another breeze
and the trade winds soft through the sighing trees
and the fat worms waiting on a dawn-bright lawn
and he names the sky his own.
But a caged bird stands on the grave of dreams
his shadow shouts on a nightmare scream
his wings are clipped and his feet are tied
so he opens his throat to sing
The caged bird sings
with a fearful trill
of things unknown
but longed for still
and his tune is heard
on the distant hill
for the caged bird
sings of freedom.
on the back of the wind
and floats downstream
till the current ends
and dips his wings
in the orange sun rays
and dares to claim the sky.
But a bird that stalks
down his narrow cage
can seldom see through
his bars of rage
his wings are clipped and
his feet are tied
so he opens his throat to sing.
The caged bird sings
with fearful trill
of the things unknown
but longed for still
and his tune is heard
on the distant hill for the caged bird
sings of freedom
The free bird thinks of another breeze
and the trade winds soft through the sighing trees
and the fat worms waiting on a dawn-bright lawn
and he names the sky his own.
But a caged bird stands on the grave of dreams
his shadow shouts on a nightmare scream
his wings are clipped and his feet are tied
so he opens his throat to sing
The caged bird sings
with a fearful trill
of things unknown
but longed for still
and his tune is heard
on the distant hill
for the caged bird
sings of freedom.
Monday, May 28, 2018
Poem: The Road Not Taken
The Road Not Taken - Robert Frost
Two roads diverged in a yellow wood,
And sorry I could not travel both
And be one traveler, long I stood
And looked down one as far as I could
To where it bent in the undergrowth;
Then took the other, as just as fair,
And having perhaps the better claim,
Because it was grassy and wanted wear;
Though as for that the passing there
Had worn them really about the same,
And both that morning equally lay
In leaves no step had trodden black.
Oh, I kept the first for another day!
Yet knowing how way leads on to way,
I doubted if I should ever come back.
I shall be telling this with a sigh
Somewhere ages and ages hence:
Two roads diverged in a wood, and I—
I took the one less traveled by,
And that has made all the difference.
And sorry I could not travel both
And be one traveler, long I stood
And looked down one as far as I could
To where it bent in the undergrowth;
Then took the other, as just as fair,
And having perhaps the better claim,
Because it was grassy and wanted wear;
Though as for that the passing there
Had worn them really about the same,
And both that morning equally lay
In leaves no step had trodden black.
Oh, I kept the first for another day!
Yet knowing how way leads on to way,
I doubted if I should ever come back.
I shall be telling this with a sigh
Somewhere ages and ages hence:
Two roads diverged in a wood, and I—
I took the one less traveled by,
And that has made all the difference.
In a 1926 letter to Cristine Yates of Dickson, Tennessee, asking about the line "I shall be telling this with a sigh" Frost wrote, "It was my rather private jest at the expense of those who might think I would yet live to be sorry for the way I had taken in life."
Saturday, May 26, 2018
Poem: There is a life force within your soul
There is a life-force within your soul
There is a life-force within your soul, seek that life.
There is a gem in the mountain of your body, seek that
mine.
O traveler, if you are in search of That
Don't look outside, look inside yourself and seek That.
There is a gem in the mountain of your body, seek that
mine.
O traveler, if you are in search of That
Don't look outside, look inside yourself and seek That.
Excerpt from Rumi, 'Thief of Sleep' translated by by Shahram Shiva
Friday, May 25, 2018
Poem - There is a Way, Rumi
There is a Way - Rumi
There is a way between voice and presence
where information flows.
In disciplined silence it opens.
With wandering talk it closes.
where information flows.
In disciplined silence it opens.
With wandering talk it closes.
Excerpt from the translations of Rumi by Coleman Barks
Thursday, May 24, 2018
Poem: This We Have Now, Rumi
This we Have Now - Rumi
This we have now
is not imagination.
This is not
grief or joy.
Not a judging state,
or an elation,
or sadness.
Those come and go.
This is the presence that doesn't.
is not imagination.
This is not
grief or joy.
Not a judging state,
or an elation,
or sadness.
Those come and go.
This is the presence that doesn't.
Excerpt from the translation of Rumi by Coleman Barks.
Wednesday, May 23, 2018
Poem: Moving Water, Rumi
Moving Water - Rumi
When you do things from your soul, you feel a river
moving in you, a joy.
When actions come from another section, the feeling
disappears.
Don't let others lead you. They may be blind or, worse, vultures.
Reach for the rope of God. And what is that? Putting aside self-will.
Because of willfulness people sit in jail, the trapped bird's wings are tied,
fish sizzle in the skillet.
The anger of police is willfulness. You've seen a magistrate
inflict visible punishment.
Now see the invisible. If you could leave your selfishness, you
would see how you've been torturing your soul. We are born and live inside black water in a well.
How could we know what an open field of sunlight is?
Don't insist on going where you think you want to go. Ask the way to the spring. Your living pieces will form a harmony.
There is a moving palace that floats in the air with balconies and clear water flowing through, infinity everywhere, yet contained under a single tent.
moving in you, a joy.
When actions come from another section, the feeling
disappears.
Don't let others lead you. They may be blind or, worse, vultures.
Reach for the rope of God. And what is that? Putting aside self-will.
Because of willfulness people sit in jail, the trapped bird's wings are tied,
fish sizzle in the skillet.
The anger of police is willfulness. You've seen a magistrate
inflict visible punishment.
Now see the invisible. If you could leave your selfishness, you
would see how you've been torturing your soul. We are born and live inside black water in a well.
How could we know what an open field of sunlight is?
Don't insist on going where you think you want to go. Ask the way to the spring. Your living pieces will form a harmony.
There is a moving palace that floats in the air with balconies and clear water flowing through, infinity everywhere, yet contained under a single tent.
Excerpt from the translations of Coleman Barks
Tuesday, May 22, 2018
Poem: The Breeze at Dawn, Rumi
The Breeze at Dawn - Rumi
The breeze at dawn has secrets to tell you.
Don't go back to sleep.
You must ask for what you really want.
Don't go back to sleep.
People are going back and forth across the doorsill
where the two worlds touch.
The door is round and open.
Don't go back to sleep.
Don't go back to sleep.
You must ask for what you really want.
Don't go back to sleep.
People are going back and forth across the doorsill
where the two worlds touch.
The door is round and open.
Don't go back to sleep.
Monday, May 21, 2018
Poem - Two Kinds of Intelligence - Rumi
Two Kinds of Intelligence - Rumi
There are two kinds of intelligence: one acquired,
as a child in school memorizes facts and concepts
from books and from what the teacher says,
collecting information from the traditional sciences
as well as from the new sciences.
With such intelligence you rise in the world.
You get ranked ahead or behind others
in regard to your competence in retaining
information. You stroll with this intelligence
in and out of fields of knowledge, getting always more
marks on your preserving tablets.
There is another kind of tablet, one
already completed and preserved inside you.
A spring overflowing its springbox. A freshness
in the center of the chest. This other intelligence
does not turn yellow or stagnate. It's fluid,
and it doesn't move from outside to inside
through conduits of plumbing-learning.
This second knowing is a fountainhead
from within you, moving out.
as a child in school memorizes facts and concepts
from books and from what the teacher says,
collecting information from the traditional sciences
as well as from the new sciences.
With such intelligence you rise in the world.
You get ranked ahead or behind others
in regard to your competence in retaining
information. You stroll with this intelligence
in and out of fields of knowledge, getting always more
marks on your preserving tablets.
There is another kind of tablet, one
already completed and preserved inside you.
A spring overflowing its springbox. A freshness
in the center of the chest. This other intelligence
does not turn yellow or stagnate. It's fluid,
and it doesn't move from outside to inside
through conduits of plumbing-learning.
This second knowing is a fountainhead
from within you, moving out.
Sunday, May 20, 2018
CDC case studies of deaths from Lyme Carditis
https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6249a1.htm
(pdf - https://www.cdc.gov/mmwr/pdf/wk/mm6249.pdf)
Three Sudden Cardiac Deaths Associated with Lyme Carditis — United States, November 2012–July 2013
Weekly
December 13, 2013 / 62(49);993-996
Lyme disease* is a multisystem illness caused by Borrelia burgdorferi, a spirochete transmitted by certain species of Ixodes ticks. Approximately 30,000 confirmed and probable cases of Lyme disease were reported in the United States in 2012, primarily from high-incidence states in the Northeast (Connecticut, Delaware, Maine, Maryland, Massachusetts, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont) and upper Midwest (Minnesota and Wisconsin) (1,2).† Common manifestations include cutaneous, neurologic, and rheumatologic signs and symptoms. Symptomatic infection of the heart is rare in recognized Lyme disease cases and usually resolves promptly with appropriate antibiotic therapy. Nonetheless, cardiac involvement occasionally can cause life-threatening cardiac conduction abnormalities. During November 2012–July 2013, one woman and two men (ranging in age from 26 to 38 years) from high-incidence Lyme disease states experienced sudden cardiac death and, on postmortem examination, were found to have evidence of Lyme carditis. The three deaths were investigated by the Connecticut Department of Public Health, Massachusetts Department of Public Health, New Hampshire Department of Public Health, New York State Department of Health, and CDC. Donated corneas from two decedents had been transplanted to three recipients before the diagnosis of Lyme disease was established, but no evidence of disease transmission was found. Although death from Lyme carditis is rare, it should be considered in cases of sudden cardiac death in patients from high-incidence Lyme disease regions. Reducing exposure to ticks is the best method for preventing Lyme disease and other tickborne infections.§
Case Reports and Public Health Investigation
Patient 1. In November 2012, a Massachusetts resident was found unresponsive in an automobile after it veered off the road. No evidence of traumatic injury was found. An electrocardiogram (EKG) performed by emergency responders showed no cardiac activity, and the patient was pronounced dead at a nearby hospital. The patient had no serious preexisting medical conditions. No rash was noted at autopsy, although some atherosclerosis was present. Interviews with next-of-kin revealed that the patient had described a nonspecific illness with malaise and muscle and joint pain during the 2 weeks preceding death. The patient lived alone with a dog that was reported to have ticks frequently.
The decedent's corneas and skin, musculoskeletal, cardiac, and vascular tissues were recovered for potential transplantation. The heart was sent to tissue bank A for valve recovery. Microscopic examination of cardiac tissue found extensive myocarditis with mixed perivascular lymphoplasmacytic inflammation suggestive of Lyme carditis. A postmortem serum sample tested at CDC yielded serologic evidence of recent infection with B. burgdorferi, reacting strongly in both whole cell sonicate (WCS) and C6 enzyme immunoassay (EIA), and against all three scored bands (23 kDa, 39 kDa, and 41 kDa) by immunoglobulin M (IgM) Western blot. Western blot testing for immunoglobulin G (IgG) antibodies demonstrated reactivity against four of 10 scored bands (23 kDa, 39 kDa, 41 kDa, and 45 kDa); these serologic findings were consistent with early disseminated Lyme disease.
Histopathologic evaluation of postmortem tissues at CDC also was suggestive of Lyme pancarditis (Figure 1) and abundant spirochetes were observed by Warthin-Starry silver stain (Figure 2). Spirochetes also were detected in the myocardium by immunohistochemistry (IHC). Polymerase chain reaction (PCR) assays detected B. burgdorferi in extracts of formalin-fixed, paraffin-embedded heart tissue based on outer surface protein A, flagellin, and plasminogen-binding protein gene targets. No donor tissues were transplanted.
Patient 2. In July 2013, a New York state resident experienced chest pain and collapsed at home. Cardiopulmonary resuscitation was unsuccessful, and the patient was pronounced dead at a local hospital. The patient's past medical history included a diagnosis of Wolff-Parkinson-White syndrome, a cardiac conduction abnormality. The patient had no known tick contact or rash but was reported to be a hiker. Evidence of hypertensive and atherosclerotic cardiovascular disease was noted at autopsy. The decedent's corneas and skin, musculoskeletal, vascular, and cardiac tissue were recovered for potential transplantation. Examination of cardiac tissue at tissue bank A revealed moderate diffuse, perivascular lymphoplasmacytic pancarditis, similar to that seen in patient 1. Serologic testing at CDC was consistent with recent infection with B. burgdorferi; WCS and C6 EIAs were strongly reactive, IgM Western blot demonstrated strong reactivity to all three scored bands, and IgG Western blot demonstrated reactivity to four scored bands (23 kDa, 41 kDa, 58 kDa, and 66 kDa). Rare spirochetes were identified in cardiac tissue by Warthin-Starry silver stain and IHC; heart tissues tested positive for B. burgdorferi by PCR.
Before diagnosis of B. burgdorferi infection, the decedent's corneas were transplanted to two recipients. The transplanting physicians and cornea recipients subsequently were notified of the donor's infection. Neither recipient 1 nor recipient 2 reported signs or symptoms of Lyme disease or problems with the transplanted cornea. Both recipients elected to receive antibiotic therapy with doxycycline. None of the remaining donated tissues were transplanted.
Patient 3. In July 2013, a Connecticut resident collapsed while visiting New Hampshire and was pronounced dead at a local hospital. The patient had complained of episodic shortness of breath and anxiety during the 7–10 days before death. No rash, arthralgia, or neurologic symptoms were noted. A physician consulted 1 day before death prescribed clonazepam for anxiety; an EKG was not performed, nor were any antibiotics prescribed. The patient lived on a heavily wooded lot and had frequent tick exposure; there was no known history of cardiovascular disease. Autopsy revealed myocarditis, and the medical examiner submitted heart tissues to CDC for evaluation of suspected viral myocarditis. Corneas and skin were recovered for donation, and one cornea was transplanted to recipient 3. No other tissue was transplanted. Recipient 3 was examined 1 week after corneal transplant and was recovering as anticipated. Examination of heart tissues at CDC again demonstrated diffuse mixed perivascular lymphoplasmacytic pancarditis. Warthin-Starry stain revealed spirochetes in the myocardium, and IHC and PCR assays confirmed the spirochete as B. burgdorferi. WCS and C6 EIAs were positive, IgM Western blot was positive for all three scored bands, and IgG Western blot demonstrated reactivity to one scored band (41 kDa).
The eye bank was informed of the Lyme disease status of the donor and the recommendations for therapy. Before notification of the Lyme disease status of the donor, recipient 3 died of unrelated causes. No tissues or serum from recipient 3 were available for evaluation.
Reported by
Gregory Ray, MD, Thadeus Schulz, MD, Wayne Daniels, DO, Cryolife, Inc. Kennesaw, GA. Elizabeth R. Daly, MPH, New Hampshire Dept of Health and Human Svcs; Thomas A. Andrew, MD, New Hampshire Office of the Chief Medical Examiner. Catherine M. Brown, DVM, Massachusetts Dept of Public Health; Peter Cummings, MD, Massachusetts Office of the Chief Medical Examiner. Randall Nelson, DVM, Matthew L. Cartter, MD, Connecticut Dept of Public Health. P. Bryon Backenson, MS, Jennifer L. White, MPH, Philip M. Kurpiel, MPH, Russell Rockwell, PhD, New York State Dept of Health; Andrew S. Rotans, MPH, Christen Hertzog, Linda S. Squires, Dutchess County Dept of Health; Jeanne V. Linden, MD, Wadsworth Center, New York State Dept of Health; Margaret Prial, MD, Office of the Medical Examiner, Orange County, New York. Jennifer House, DVM, Pam Pontones, MA, Indiana State Dept of Health. Brigid Batten, MPH, Dianna Blau, DVM, PhD, Marlene DeLeon-Carnes, Atis Muehlenbachs, MD, PhD, Jana Ritter, DVM, Jeanine Sanders, Sherif R. Zaki, MD, PhD, Div of High-Consequence Pathogens and Pathology; Paul Mead, MD, Alison Hinckley, PhD, Christina Nelson, MD, Anna Perea, MSc, Martin Schriefer, PhD, Claudia Molins, PhD, Div of Vector-Borne Infectious Diseases, National Center for Emerging and Zoonotic Infectious Disease; Joseph D. Forrester, MD, EIS Officer, CDC. Corresponding contributor: Joseph D. Forrester, jforrester@cdc.gov, 970-266-3587.
Editorial Note
This report describes three cases of sudden cardiac death associated with Lyme carditis, with subsequent transplantation of corneas from two of the decedents into three recipients. Only rarely has death been attributed to Lyme carditis (3–6), and review of pathology reports at tissue bank A did not identify any additional confirmed cases among 20,000 cardiac specimens received since 2004. Whether the preexisting heart conditions found in two patients increased their risk for death is unclear.
Borrelia burgdorferi has been shown to affect all layers of the heart, but tends to spare the great vessels and heart valves (7). Inflammation is characteristically diffuse, perivascular, lymphohistiocytic, and plasma cell-rich. Spirochetes can be found within the myocardial cellular infiltrates; IHC and PCR testing can provide additional evidence of infection. Although Lyme carditis usually is present in conjunction with other features of the disease, such as erythema migrans, arthritis, or neurologic disease, it can be observed independently (8). The most common cardiac manifestation is atrioventricular block, which can fluctuate between first, second, and third degree (7,8). Second-degree or third-degree atrioventricular block occurs in approximately 0.8% of all Lyme disease cases reported to CDC (2). Symptoms of atrioventricular block, including lightheadedness, palpitations, shortness of breath, chest pain, and syncope can occur 4 days to 7 months after onset of disease, with a median of 21 days (7,8). With appropriate therapy (9), prognosis is excellent, and signs of cardiac involvement typically resolve within 1–6 weeks, depending on the degree of conduction disturbance (10). Some cases of complete heart block might require temporary pacing.
Although no cases of Lyme disease transmission through organ or tissue transplantation have been reported, the identification of organisms in tissue suggests the risk for transmission could exist. Ophthalmologic manifestations of Lyme disease are rare but can involve any of the ocular structures and occur during any stage of Lyme disease.¶ Given the rarity of ocular Lyme disease, and of corneal Lyme disease in particular, and the absence of ocular symptoms in the deceased patients, the need for antibiotics in this setting was equivocal. However, if administered, oral doxycycline would be expected to penetrate eye structures well.
Medical examiners and pathologists should be aware that Lyme carditis is a potential, albeit rare, cause for sudden cardiac death in persons from high-incidence Lyme disease areas. Diffuse, mixed perivascular lymphoplasmacytic infiltrates seen on pathologic examination of heart tissue from patients who have sudden cardiac death in high-incidence Lyme disease areas should prompt serologic evaluation for Lyme disease and further histopathologic examination for spirochetes, including IHC evaluation and PCR. Lyme disease is a nationally notifiable disease; all suspected cases of fatal Lyme carditis should be reported to state or local public health authorities, and the cases should be investigated.
Prompt recognition and early, appropriate therapy for Lyme disease is essential. Health-care providers should ask patients with suspected Lyme disease about cardiac symptoms and obtain an EKG if indicated. Conversely, they should ask patients with unexplained heart block about possible exposure to infected ticks. Health-care providers also should remind their patients of steps to prevent infection, including use of repellent, daily tick checks, prompt showering after potential exposure, and landscape management. The three deaths described in this report underscore the need for better methods of primary prevention of Lyme disease and other tickborne infections.
References
- CDC. Notice to readers: final 2012 reports of nationally notifiable infectious diseases. MMWR 2013;62:669–82.
- CDC. Surveillance for Lyme disease—United States, 1992–2006. MMWR 2008;57(No. SS-10):1–9.
- Cary NR, Fox B, Wright DJ, Cutler SJ, Shapiro LM, Grace AA. Fatal Lyme carditis and endodermal heterotopia of the atrioventricular node. Postgrad Med J 1990;66:134–6.
- Marcus LC, Steere AC, Duray PH, Anderson AE, Mahoney EB. Fatal pancarditis in a patient with coexistent Lyme disease and babesiosis. Demonstration of spirochetes in the myocardium. Ann Intern Med 1985;103:374–6.
- Tavora F, Burke A, Li L, Franks TJ, Virmani R. Postmortem confirmation of Lyme carditis with polymerase chain reaction. Cardiovasc Pathol 2008;17:103–7.
- Reimers CD, de Koning J, Neubert U, et al. Borrelia burgdorferi myositis: report of eight patients. J Neurol 1993;240:278–83.
- Steere AC, Batsford WP, Weinberg M, et al. Lyme carditis: cardiac abnormalities of Lyme disease. Ann Intern Med 1980;93:8–16.
- Fish AE, Pride YB, Pinto DS. Lyme carditis. Infect Dis Clin N Am 2008;22:275–88.
- Wormser GP, Dattwyler RJ, Shapiro ED, et al. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 2006;43:1089–134.
- McAlister HF, Klementowicz PT, Andrews C, Fisher JD, Feld M, Furman S. Lyme carditis: an important cause of reversible heart block. Ann Intern Med 1989;1110:339–45.
* Additional information available at http://www.cdc.gov/lyme.
† Additional information regarding how many persons receive a diagnosis each year of Lyme disease is available at http://www.cdc.gov/lyme/faq/index.html#humancases.
§ Additional information available at http://www.cdc.gov/lyme/prev/index.html.
¶ Additional information available at http://www.sciencedirect.com/science/article/pii/S0161642099001281.
What is already known on this topic?
Carditis with heart block is a known but uncommon complication of early disseminated Lyme disease that is generally treated effectively with appropriate antibiotic therapy. Four deaths from Lyme carditis have been reported.
What is added by this report?
This report describes three new cases of sudden cardiac death associated with Lyme carditis. The decedents were aged 26 to 38 years and lived in high-incidence Lyme disease areas.
What are the implications for public health practice?
Pathologists and medical examiners should be aware that Lyme carditis can be a cause of sudden cardiac death. All suspected cases of fatal Lyme carditis should be reported to state or local public health authorities, and the cases should be investigated. Physicians and health-care providers should ask patients with suspected Lyme disease about cardiac symptoms, and conversely, ask patients with acute, unexplained cardiac symptoms about possible tick exposure and symptoms of Lyme disease. Clinicians should encourage all patients to practice recommended tick bite prevention strategies.
FIGURE 1. Hematoxylin and eosin stain at 6.25X magnification demonstrating interstitial perivascular lymphoplasmacytic pancarditis in postmortem tissue of one of three patients whose death was associated with Lyme carditis — United States, 2013
Alternate Text: The figure above shows Hematoxylin and eosin stain, demonstrating interstitial perivascular lymphoplasmacytic pancarditis in postmortem tissue of one of three patients whose death was associated with Lyme carditis in the United States in 2012.
FIGURE 2. Warthin-Starry stain of cardiac tissue at 158X magnification demonstrating Borrelia burgdorferi spirochetes (arrow) in one of three patients whose death was associated with Lyme carditis — United States, 2013
Alternate Text: The figure above shows a Warthin-Starry stain of cardiac tissue demonstrating Borrelia burgdorferi spirochetes in one of three patients whose death was associated with Lyme carditis during November 12–July 2013.
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Saturday, May 19, 2018
System failure in a heart hospital in the US
https://www.houstonchronicle.com/news/investigations/article/Heart-Failure-patients-suffer-at-St-Lukes-Houston-12916224.php
Fabled past, poor results
Heart Failure
At St. Luke’s in Houston, patients suffer as a renowned heart transplant program loses its luster
By Mike Hixenbaugh, Houston Chronicle
and Charles Ornstein, ProPublica
Published on Wednesday, May 16, 2018, at 5 a.m.
The anonymous letter reached Judy Kveton in March 2017. Nearly two months earlier, her husband's failed heart transplant at Baylor St. Luke's Medical Center had led to a week of follow-up surgeries, a pair of devastating strokes and then, his death. The donor heart that doctors had implanted in David Kveton was "just not acting right," Judy remembers the surgeon, Dr. Jeffrey Morgan, telling her hours before she decided to remove her husband from life support.
The letter mailed to her home in nearby Fort Bend County — one page, single-spaced and folded into an envelope with no return address — told a different story.
ABOUT THE SERIES
This story is the result of a collaboration between the Chronicle and ProPublica, an independent nonprofit newsroom based in New York. Mike Hixenbaugh is an investigative reporter for the Chronicle. Charles Ornstein is a senior editor at ProPublica.
'They turned us away'
Baylor St. Luke's in Houston was known for handling complex heart transplants. But when Travis Hogan was a patient there, he didn't know that the program was undergoing a series of dramatic changes. He never got his heart. Click here to read the story.
Baylor St. Luke's in Houston was known for handling complex heart transplants. But when Travis Hogan was a patient there, he didn't know that the program was undergoing a series of dramatic changes. He never got his heart. Click here to read the story.
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A top heart surgeon's quest to make medical history, and years of undisclosed trouble
A top heart surgeon's quest to make medical history, and years of undisclosed trouble
It said St. Luke's has had some of the worst heart transplant outcomes in the country. It said other physicians had specifically voiced concerns about Morgan, the program's lead surgeon. And it said, despite "numerous complications, deaths, and poor outcomes," administrators had not done enough to correct the problems.
"I feel that David was not given the opportunity he deserved after struggling with his disease for so long."
Signed, "Concerned."
The note left Judy in tears. Although it didn't specify what went wrong with her husband's transplant, it made her doubt the reasons she and her husband chose St. Luke's more than a decade earlier, when his heart began to fail. The Houston hospital, which is affiliated with Baylor College of Medicine and the Texas Heart Institute, has long held itself out as one of the best in the world for heart surgery.
But in recent years, the famed program has performed an outsized number of transplants resulting in deaths or unusual complications, has lost several top physicians and has scaled back its ambition for treating high-risk patients, all the while marketing itself based on its storied past, an investigation by the Houston Chronicle and ProPublica reveals.
About two months after David Kveton's death, his wife Judy Kveton received an anonymous letter stating that there were problems with David's heart transplant. (Elizabeth Conley/Houston Chronicle)
St. Luke's heart transplant survival rate, the most important measure of a program's quality, now ranks near the bottom nationally, according to the most recently published data. Among St. Luke's patients who received a new heart between the summer of 2014 and the end of 2016, just 85 percent survived at least one year, compared to 91.4 percent nationally.
Put another way, twice as many St. Luke's patients died within a year as would have been expected, taking into account patient characteristics and illnesses.
In January, the federal Centers for Medicare and Medicaid Services cited the heart transplant program for its significantly worse-than-expected outcomes and threatened to cut off Medicare funds in August if the problems were not fixed, according to a letter obtained by ProPublica and the Chronicle. The program has since submitted a plan of correction and avoided the loss of federal funds.
Many of the program's troubles are spelled out in data published by the Scientific Registry of Transplant Recipients, which is funded by the U.S. Department of Health and Human Services to track and analyze transplant outcomes. SRTR reports, released twice a year, serve as a scorecard for transplant programs, capturing and presenting data on patient survival that spans a rolling 30-month period.
The hospital says it made changes when outcomes began to decline. After a string of transplant patient deaths in 2015, the program hired Morgan as its surgical director and became more conservative, removing some higher-risk patients from its waiting list. It is also more selective than its peers in its acceptance of donor hearts. Since then, program leaders said, the survival rate has improved.
But the program has struggled in other ways.
In one of Morgan's first transplant surgeries at St. Luke's, in early 2016, he sewed shut one of two major veins that carry blood back to the heart, and the patient died a few weeks later, according to six medical professionals familiar with the case.
In another patient's transplant a year later, Morgan stitched through the other major vein, according to the patient's cardiologist, though Morgan said the man's previous cancer treatments complicated the case. After the initial surgery, the blocked vein caused blood to pool in the patient's head, leading to an emergency repair, weeks of follow-up operations, a three-month hospital stay and ongoing health struggles, including kidney failure.
Then, in January of this year, a heart defibrillator malfunctioned in the operating room during a critical stage of a patient's transplant. Although the hospital said "a backup defibrillator was nearby and readily available," the surgeon in that case, Dr. Masahiro Ono, described it differently. He said in an interview that the backup was not easily accessible, forcing him to pump the man's new heart by hand for nearly 10 minutes.
"I cannot control that part as the surgeon," Ono said of the device failure, which he said led to an internal investigation. "I tried my best to preserve the function of the heart, but it couldn't make it."
The 52-year-old patient died in March after undergoing more than a dozen operations and suffering numerous complications, including strokes, serious infections and organ failure.
Meanwhile, more St. Luke's patients have lingered in the hospital for weeks or months following their transplants, a sign of slow recovery or possible complications, experts say. Between mid-2016 and mid-2017, half of the program's heart recipients stayed in the hospital for 27 days or longer after transplant, compared to 16 days nationally. That ranked third longest of 125 programs in the country.
HEART FAILURE: As wait for new heart got longer, patient grew sicker
As the problems at St. Luke's deepened, some doctors at the hospital raised concerns with administrators but said they were ignored. Some even began referring transplant patients to other programs.
Several top doctors have left in recent years, and later in May, Ono plans to leave for a leadership post at a smaller program in San Antonio. The losses have further diminished care, longtime staffers say.
Despite these problems, the hospital continued to market itself as a standout, boasting above-average survival rates and high transplant volume.
A few months after David Kveton's death, the hospital posted a video online of Morgan touting the center's excellence: "I truly believe that patients here get first-rate care that's unmatched by any other institution locally, regionally, nationally or internationally," he said, before asserting that the program had performed the most heart transplants in the country, which is not true, and that it had above-average outcomes. The hospital's website also featured charts that provided a misleading picture of the program's recent performance.
The video and charts were removed a day after reporters questioned hospital administrators about them in January.
In an interview that month and in response to subsequent written questions, transplant program leaders acknowledged the poor outcomes but said the spike in patient deaths was confined to 2015, during a time of transition.
Transplant program leaders provided data showing that the one-year survival rate for patients who underwent transplants since Morgan's arrival in 2016 was about 94 percent, though the numbers do not capture the plight of patients who survived after having serious complications.
"We only have had one year with below-expected outcomes in the recent past, 2015, and that's been corrected," Morgan said.
Hospital officials said if St. Luke's has lagged behind its peers in measures of quality — including survival rates — it is primarily because the program treats older, sicker patients compared to many other programs. They also said more of their patients lack insurance coverage or the means to pay for rehabilitation, leading to longer hospital stays, though publicly available data shows that their patients have similar coverage compared to other hospitals.
"Heart transplant patients often are very sick individuals who have undergone years of prior heart procedures, and sometimes even previous transplants or device implants to keep their heart beating, and often battle other illnesses and diseases — all of which can complicate a heart transplant," the hospital said in a statement.
Officials said the same was true of each of the patients who suffered poor outcomes and whose families spoke to reporters for this story.
Other programs have found ways to post better results while performing transplants for critically ill patients.
Houston Methodist hospital, a short walk from St. Luke's at the Texas Medical Center, performs transplants on heart failure patients who, overall, are older and in more dire condition than patients at St. Luke's, according to SRTR data. Yet Methodist patients who received transplants from mid-2014 to the end of 2016 were significantly more likely to survive a year afterward.
"St. Luke's and Texas Heart Institute really paved the way for complex heart surgery, particularly heart transplants, to become a routine lifesaving procedure," said Dr. Tom MacGillivray, who took over as the lead heart transplant surgeon at Houston Methodist in 2016 after nearly two decades at Harvard University and Massachusetts General Hospital.
"To see them having trouble, that should be a concern for all of us."
Judy Kveton (pronounced KWEET-on) remembers feeling awestruck by the history of St. Luke's each time she entered the conjoined buildings it shares with the Texas Heart Institute. A museum near the entrance is filled with medical artifacts from past achievements.
Broken Hearts
It was here that famed surgeon Denton Cooley performed some of the world's first heart transplants back in the 1960s, and where his protégé, Dr. O.H. "Bud" Frazier, has pursued a lifelong quest to develop a complete mechanical replacement for the human heart.
Decades later, the hospital has continued to promote itself based on those triumphs.
That's why, when David Kveton, a construction worker from Pleak in Fort Bend County, had an opportunity to transfer to another hospital in 2012, he and his wife decided to stick with St. Luke's. His cardiologist, Dr. Biswajit Kar, was part of a team of physicians — including two other cardiologists and a surgeon — hired away from St. Luke's that year to start a heart transplant unit down the street at Memorial Hermann Heart & Vascular Institute.
"He tried to get us to come with him," Judy said. "But we thought, 'This is the best heart hospital in the world. Why risk transferring to someplace just getting started?' "
Many St. Luke's patients made the opposite choice. In 2013, the year after the doctors left, St. Luke's transplant cases dropped by more than half, to 25, as dozens of heart failure patients shifted to the new program.
Judy said she observed declines in her husband's care at St. Luke's in the years that followed, a period that coincided with other major changes at the hospital. A year after the team left for Memorial Hermann, St. Luke's longtime owner, the Episcopal Diocese of Texas, sold the hospital to Catholic Health Initiatives, a Colorado-based nonprofit hospital chain.
In 2014, CHI entered into an ambitious agreement with Baylor College of Medicine to build a new medical campus, including a $916.8 million, 650-bed hospital to replace its aging facility in the Texas Medical Center.
CHI's rapid expansion was too much, too fast, and the chain amassed deep debt, according to the nation's two largest credit-rating services. Last year, they downgraded CHI's debt, with one specifically citing the organization's "weak (financial) performance" in Houston as a cause for concern. A series of layoffs, staffing changes and other cost-cutting decisions since then hurt patient care at the chain's flagship Texas hospital, according to several current and former St. Luke's physicians. More changes could be afoot: CHI is in the midst of merging with another chain to become one of the nation's largest nonprofit hospital operators.
Gay Nord, the hospital's president, denied that staff cuts affected care in the heart transplant unit, but in 2015, two years after the CHI purchase, the program took a dramatic fall. Among 14 patients who received a heart transplant in the first six months, five died in less than a year, far more than would be expected. The program slowed after that, performing just six transplants in the second half of the year; one recipient died. (Doctors performed another that year as part of a multiorgan transplant, which doesn't count toward outcome figures.)
Muta Melton was among the deaths. She got a call on her 48th birthday, May 31, to let her know St. Luke's was receiving a heart for her. After initial complications, the outlook seemed bright. Melton was moved out of intensive care and even started walking and putting on her own clothes. "She was so excited to come home," said her mother, Sheila Cram. "She looked good."
Melton never left the hospital. She died six weeks after her transplant of a raging infection. "Things went downhill very, very quickly," said Melton's daughter, Roseanna McLaren. "I was not expecting her to pass at all. It happened, I don't know, in maybe 36 hours."
Both McLaren and Cram said they were unaware of the program's recent struggles until they spoke to a reporter. "I thought that was supposed to be the best hospital," Cram said. "That's what I was told. That's what everybody says. But evidently not."
Behind the scenes, the program was reeling. Dr. Hari Mallidi, one of its leading surgeons, left that summer for a position at Brigham and Women's Hospital in Boston, a teaching hospital affiliated with Harvard Medical School.
Mallidi had come to St. Luke's three years earlier, just before the team of doctors left for Memorial Hermann. When he started, he said, outcomes were "trending in the wrong direction," but he instituted "some basic changes, and things got a lot better." A review of SRTR data confirms that the program's one-year survival rate improved during Mallidi's tenure leading up to 2015.
The CHI acquisition in 2013 and the resulting transition, he said, caused "a lot of bumps in the road," which he declined to specify. Mallidi said he concluded, even before the string of patient deaths in 2015, that "leaving was better for my own academic development."
Dr. Hari Mallidi
Around that same time, Frazier, the surgeon who started the transplant program in 1982 and had reportedly performed more transplants than anyone in the world, also stopped operating regularly.
At the start of 2016, a 42-year-old surgeon arrived from Detroit to take over.
Morgan was an unconventional pick to lead a heart and lung transplant program as prominent as St. Luke's. Top programs typically seek surgical leaders who have elite skills in the operating room while also conducting groundbreaking research.
An unconventional choice
But Morgan was relatively early in his career, having been the lead surgeon on just 18 heart transplants in the previous five years at Henry Ford Hospital in Detroit, according to numbers provided by St. Luke's. The program is smaller and less prestigious and had somewhat worse-than-expected outcomes toward the end of Morgan's time there.
Before leaving, Morgan was assistant director for heart transplants and the primary surgeon for mechanical heart pumps.
The team at St. Luke's saw potential. Dr. Billy Cohn, a longtime heart surgeon at St. Luke's who now runs a medical device innovation lab for Johnson & Johnson at the Texas Medical Center, led the hiring committee that selected Morgan.
They chose him, he said, despite his relative lack of surgical experience, because he was "an academic superstar," having published numerous studies about advanced heart failure and having served as a reviewer and editor for medical journals.
Cohn stopped operating full time by late 2016 but remains on staff at Texas Heart Institute and Baylor, and he is still called upon sometimes to assist with complex surgeries.
"It was a bold move for him to come in and take this job," Cohn said of Morgan. "It was a bold move for us to offer it to him."
Some of Morgan's work in Detroit has been called into question. Since moving to Houston, he has been named in two malpractice lawsuits in Michigan's 3rd Circuit Court.
In one, filed in March 2017, a widow alleged that Morgan made a fatal error during a December 2014 operation to implant a pair of mechanical heart pumps in her husband, leading to an embolism in his brain. The hospital agreed to settle the case for an undisclosed amount of money a month after it was filed. An attorney for the patient's widow declined to comment.
In another, a patient accused Morgan of failing to properly perform his quadruple heart bypass in July 2015. Later, another physician determined the original bypass surgery by Morgan "was performed incorrectly" and needed to be redone, according to the complaint filed this January. Morgan has been dropped as a named party in the lawsuit, although the case centers on his actions and continues against the hospital. The hospital denied the allegations in a March 1 court filing. The patient's lawyer declined to comment, as did the hospital.
"To the best of my knowledge, the medical care that I provided in these cases met or exceeded applicable standards," Morgan wrote in response to written questions.
Cohn acknowledged Morgan has made surgical "errors" since coming to St. Luke's, including in his first weeks on the job, when he stitched through a major vein while implanting a new heart in a patient, blocking the flow of blood. Cohn remembered how physicians tried to figure out what had gone wrong when the patient's condition began to decline after the transplant.
The patient died a few weeks later.
"Was it because he was cavalier, or he didn't care, or he wasn't skilled?" Cohn said. "It was none of those things. He just cut in the wrong place."
Morgan said federal patient-privacy requirements prevented him from discussing the case without the family's approval.
Cohn and three other medical professionals also confirmed that Morgan stopped performing lung transplants not long after his arrival after some of his initial patients experienced complications. Dr. Steve Singh, another cardiac surgeon who has since left, and then Ono took over until a new lung transplant surgeon was hired a year later.
"Was it hubris for Jeff to say, 'I'm going to do lungs?' " Cohn said. "We put him in that position and said, 'You're the chief, man. Go for it.' We handed him the reins. Was that our error? Yeah, maybe we should have said, 'Dude, you don't have the [experience] to be a lung transplant guy. We're going to shut the program down until we find somebody.' "
Although Baylor's hiring announcement noted Morgan's expertise in treating patients with lung failure, Morgan said in response to written questions that "it is rare for a surgeon to focus on both heart and lung transplants."
Former St. Luke's cardiologist Dr. Roberta Bogaev said she asked administrators to commission an external review toward the end of Morgan's first year at the program, in late 2016, and she began referring some of her most challenging heart failure cases elsewhere.
Dr. Roberta Bogaev
"It becomes very ethically challenging to recommend transplant if you don't have that confidence level in your surgeon," Bogaev said.
Surgical leadership was not her only concern. She said the loss of many experienced nurses and specialists following CHI's acquisition — including in infectious disease, critical care and pathology — likely led to poorer transplant outcomes. And the policies of new hospital leadership restricted physicians' ability to pursue innovative research, she said.
Bogaev left the hospital in early 2017 after taking a job in Virginia, primarily to be closer to family.
"I can tell you I have patients who would not be alive today if not for the program at Texas Heart Institute, and I'm a better physician because of the time I spent there," Bogaev said. "But there was a clear change in direction of the whole program and the spirit of the program. And certainly the staff felt it, the patients felt it, and I am confident it caused a lot of the physicians as well as patients" to leave.
Dr. Deborah Meyers, the medical director of the heart failure program at St. Luke's until early 2017, also raised concerns both before and after Morgan arrived.
"I had multiple conversations with multiple medical administrators during my tenure who were unwilling to get an external review to address the problems and unwilling to make substantial changes," she said. Meyers, who now practices cardiology in Salinas, California, said she also referred some of her patients in 2016 to other hospitals because of her concerns.
"I told a couple of the patients [whom] I just loved that, 'I want you to go to other institutions. I don't feel good about our program.' That's true. And that's a terrible thing."
She likened those conversations to "a mother saying somebody else is going to take better care of you than I can. It's a heartbreaking situation."
Dr. Todd Rosengart, the chair of surgery at Baylor College of Medicine, played a leading role in hiring Morgan and said he considers him among "a number of luminaries" of surgery he has recruited to Houston in recent years. Morgan, like most physicians who practice at St. Luke's, is an employee of Baylor, where he is a professor and chief of cardiothoracic transplantation.
Dr. Todd Rosengart
Dr. Paul Klotman, the medical school's president and chief executive, said in a statement that Morgan "has proven to be a talented transplant surgeon with excellent outcomes."
The hospital also agreed to put reporters in touch with heart transplant patients who were pleased with the care they received, including Karim Rashid, a 52-year-old investment banker. He received a transplant last Thanksgiving after suffering from a rare inflammatory condition that caused heart failure several years earlier.
"I have nothing but excellent things to say," said Rashid, who credits Morgan and his other St. Luke's physicians with saving his life.
Morgan said referrals to his program were up significantly in 2017 from a year earlier and are up again this year.
Despite the early problems, Cohn said he does not regret recruiting Morgan. He said Morgan's "surgical skills have come a long way" over the past two years, and he believes hiring him will work out in the long run, even if he never becomes one of the best in his field.
"Is it possible that someday Jeff is one of the most distinguished and experienced heart surgeons in the country?" Cohn said. "I don't think so. I don't think he's that guy. ... Mainly because he is so focused on academia, and that takes a lot of time.
"Is it possible that he will be highly respected and run a big program and do a great job? I expect so."
Judy Kveton knew nothing about Morgan's background or the concerns raised by his colleagues when Morgan walked into a waiting room in the early-morning hours of Jan. 26, 2017, following her husband's transplant.
'Turn him off'
"The surgery went well," she remembers Morgan saying. "Everything is fine."
Morgan recalls that conversation differently than Judy and three other family members who were in the room. "After the surgery, I thoroughly explained to Mrs. Kveton that her husband was critically ill and was on a lot of medication to keep his blood pressure up," he wrote in response to questions.
A day later, David Kveton was taken back into surgery. Doctors connected him to a life-support machine that circulates oxygenated blood through the body, doing the work of both the heart and lungs, in an attempt to give the new heart time to strengthen.
It was the first of several follow-up procedures that week.
"Nobody really told us anything," Judy said. "But at some point, after a few days of this, we realized something wasn't right."
The downward spiral is detailed in David's medical records: On Jan. 28, doctors inserted a balloon pump into the donor heart, an attempt to increase its pumping strength, but improvement was marginal. Three days later, a CT scan revealed he had likely suffered a stroke, though family members say they were not told of bleeding in his brain.
Six days after the transplant, Morgan surgically removed David from the bypass machine, hoping the heart had grown strong enough. Soon after, he developed an irregular heart rhythm and had to be taken back to an operating room, where Morgan reconnected him.
Afterward, Morgan called Judy, who had gone home for the night to rest: "Everything went fine," she remembers him saying. "But we're going to have to take out this heart, and we're going to have to put in an artificial heart until we get him another transplant."
She was stunned. After all her husband had been through, would they really start over?
It was the last time she spoke to the surgeon. Early the next morning, a nurse called to tell her something had gone wrong and that she and her children should make their way to the hospital. Once they arrived, the nurse quietly told Judy her husband had suffered another stroke. Hours later, a neurologist confirmed David might never recover normal brain function. That's when his family decided to withdraw life support.
"Turn him off," Judy remembers saying. "My husband wouldn't have wanted to live like this."
He died on Feb. 2, 2017, at the age of 64.
That afternoon, back at home, Judy said she got a call from Frazier, the world-renowned transplant surgeon who remains active in research at Texas Heart Institute and whose image is prominent throughout St. Luke's online marketing materials. He asked for permission for the hospital to perform an autopsy on her husband:
"Miss Kveton, we haven't lost a patient this soon after a transplant like this since the '80s," she remembers Frazier telling her. "This shouldn't have happened. I would like your permission to go in, I want to take that heart out. I want to find out, did we twist something putting it in? Or was it not screened properly?"
In a written response to questions, Frazier said he recalls calling Judy but not the details of the conversation. He said it's common to perform autopsies when patients die after receiving transplants to "learn as much as possible from our surgeries, no matter the outcome."
Judy gave permission, then never heard back. Instead, she received a bill for more than $1 million for the transplant and her husband's final week in the hospital.
For reasons unknown to her, Medicare was refusing to pay, and now St. Luke's billing department was writing to collect.
Two days after David Kveton's funeral, Morgan was at the helm of another transplant that went poorly.
A quest for answers
Lazerick Eskridge had been on the heart waiting list at St. Luke's since 2015, a little more than two years, when he and his wife, Lisa, received word the hospital had a heart for him on the night of Feb. 8, 2017.
Lazerick, a Navy veteran, also had been given an opportunity to transfer to Memorial Hermann years earlier when his cardiologist, Kar, left to start the transplant program there. Like the Kvetons, the Eskridges couldn't imagine leaving a hospital as renowned as St. Luke's.
Finally, it seemed, their patience was about to pay off.
The morning of the surgery, they were greeted by Ono, the surgeon who soon plans to leave St. Luke's. He told them he would be performing the transplant. But later that night, after hours of surgery, it was Morgan — a doctor the Eskridges had never met — who emerged from the operating room. Ono, Lisa was told later, had been tapped for a lung transplant.
Morgan told her "everything was fine," Lisa said. "I was so relieved and so thankful."
Less than an hour later, a nurse arrived in the waiting room with a much different message: Something was wrong; her husband was back in surgery and in critical condition.
Although Morgan said he thoroughly explained the situation to the family, Lisa said she doesn't remember anyone telling her specifically what had gone wrong that night. All she knew was that her husband's new heart wasn't pumping enough blood, and something had caused his head to swell grotesquely. Later, when she visited him in the intensive care unit, she said his eyes were bulging from his face.
"It didn't even look like him," Lisa said.
Over the next several days, Lazerick underwent a series of follow-up surgeries and procedures to remove excess fluid. Like David Kveton, he was put on the heart-lung bypass machine for several days while doctors worked — doing what, Lisa was not sure.
Finally, after a week, Lazerick emerged with a marginally functioning heart — but also suffering from kidney failure, multiple infections and an injured right diaphragm that now prevents his lung from inflating completely. He remained in the hospital for three months and lost more than 70 pounds.
The year since then has been a struggle, he said.
Lazerick, now 47, had long suffered from congestive heart failure — a side effect of chemotherapy treatments two decades ago — but his kidneys and lungs had always been fairly strong. Since his heart transplant, he has been in and out of the hospital with breathing difficulties, including in December, when he spent weeks connected to a ventilator. When he's not in the hospital, his days are consumed with medical appointments.
He must undergo dialysis three times a week, a treatment that flushes toxins from his body — doing the work of his failed kidneys. The exhausting cycle leaves him bedridden half the week; the other days are spent at physical therapy sessions.
The Eskridges were surprised to learn from a reporter that the federal government had cited St. Luke's for poor heart transplant outcomes. That prompted them last month, more than a year after the transplant, to ask Lazerick's cardiologist, Dr. Joggy George, if he could tell them more about what had gone wrong.
A Chronicle reporter sat in on the appointment at George's office in St. Luke's medical tower, a short walk from the hospital. What the doctor said left Lisa in tears.
George, a private practice transplant cardiologist, had stopped by the operating room to check on Lazerick shortly after his transplant. The medical team, he said, was preparing to move him back onto the operating table and reopen his chest.
George said he was later told by others in the room that a major vein connected to the heart must have been stitched through during the transplant, effectively pinching the vessel shut and causing blood to back up in Lazerick's head.
George explained that many of Lazerick's problems since then — his kidney failure, his breathing struggles, his inability to keep food down — may trace back to the blocked vein and the string of emergency operations and complications that followed.
"I realize this is very difficult for you to talk about and think about," George told the Eskridges, before handing Lisa a box of tissues. "This was probably the darkest hour of your lives."
After it became clear that blood wasn't flowing into Lazerick's new heart, Morgan performed an emergency procedure, connecting a smaller vein directly to the donor organ and permanently bypassing his superior vena cava. Because the bypass vein is smaller, George said Lazerick is at a higher risk of developing clots and must take blood thinners daily.
"I personally have not seen that happen before," George said, explaining that it's unusual for a major vein to be sutured closed during a transplant.
Medical records that the hospital released to the family, more than 6,800 pages in total, corroborate much of what George said, though nowhere do they explain how the vein became blocked.
HELP US INVESTIGATE: Are you an employee, patient or a family member of a patient at the Texas Medical Center? We'd like to hear from you about your experience
"It's kind of a shock," Lazerick said, "to learn something like this could happen to you and nobody tells you about it."
In a statement, Morgan said the vein tissue was "severely abnormal" because of Lazerick's past cancer treatments and also was distorted by wires attached to the cardiac devices in his chest. Morgan said he used sutures to reinforce the vein's connection to the heart, but due to "concern for narrowing," he performed the bypass, which continues to work.
In defending its continued promotion of the heart transplant program as a national leader, St. Luke's officials provided data showing that patient survival rates rebounded after Morgan's arrival.
In February, Lazerick marked the first anniversary of his transplant. Statistically, that made him one of the success stories.
For Judy Kveton, the past year has been a frustrating search for answers.
She has spent hours sifting through stacks of her husband's medical records, more than 2,000 pages, searching for passages that might tell her why he died. It's hard to make sense of any of it, she said, but there are clues.
'Mad as hell'
On the night of the initial surgery, an anesthesiologist, Dr. Manu Sethi, wrote a report noting that he observed complications after the transplant: "Multiple attempts to come off pump," Sethi wrote, then indicated David Kveton was receiving drugs to strengthen heart contractions and increase his blood pressure.
Two days later, a cardiologist, Dr. Ajith Nair, wrote a note in David's electronic medical record that included a hypothesis about what was causing the transplant to fail: "Suspect primary graft dysfunction, possibly due to ischemic time," Nair wrote, suggesting there may have been too much time between when the transplanted heart was removed from the donor and when it was implanted in David.
Nobody at St. Luke's ever expressed that concern to Judy, she said, and the medical records released to her didn't include any other information about the donor heart. She needed the help of a lawyer to get the hospital to release the autopsy Frazier had ordered. When she finally received a copy in October, it only seemed to raise more questions.
The St. Luke's physician who conducted the autopsy reported signs of a heart attack in the donor heart at the tip of the left ventricle. But the report didn't draw any conclusions about what factors may have led to David's death.
Judy wondered: Was there something wrong with the organ before it went into her husband?
In the fall, after talking with a reporter, she asked the United Network for Organ Sharing for details about the donor heart. She wanted to know what condition it was in, how much time passed before it was stitched into her husband's chest, how many, if any, other hospitals had rejected the organ before it reached David. The organ-sharing agency initially gave her guidance on how to request some of that information, then abruptly reversed itself, declining to provide records without a subpoena.
"I feel like the entire system is stacked against me," Judy said in January, throwing her hands up in frustration.
At least she's no longer burdened by the prospect of owing St. Luke's more than $1 million. Medicare eventually, without explanation, agreed to pay a small fraction of that amount, relieving her of any obligation.
Still, when she re-reads the anonymous letter — the one that suggests her husband wasn't given a fair shot — she grows angry that someone at St. Luke's might know what went wrong but won't tell her:
"It just makes me as mad as hell."
***
Houston Chronicle data editor Matt Dempsey and ProPublica data reportersHannah Fresques and Olga Pierce contributed to this report.
Mike Hixenbaugh is a Chronicle investigative reporter focused on health care. He recently was awarded the Associated Press Media Editors storytelling award, is a four-time Livingston Awards finalist, and in 2018 was named Star Reporter of the Year for the state of Texas. Before joining the Chronicle in 2016, he was a reporter at The Virginian-Pilot in Norfolk, Va., where his work on the military and veterans affairs was co-published with ProPublica, NBC News and the Investigative Reporting Program at UC Berkeley. He graduated from the University of Akron in 2007, before going to work for newspapers in Ohio and North Carolina. Follow him on Twitter at @Mike_Hixenbaugh. Contact him atmike.hixenbaugh@chron.com.
Charles Ornstein is a senior editor at ProPublica, overseeing its Local Reporting Network. From 2008 to 2017, he was a senior reporter covering health care and the pharmaceutical industry. Prior to joining ProPublica, he was a member of the metro investigative projects team at the Los Angeles Times. In 2004, he was a lead author on a series on Martin Luther King Jr./Drew Medical Center, a troubled hospital in South Los Angeles. The articles won the 2005 Pulitzer Prize for Public Service. He previously worked at the Dallas Morning News, where he covered health care on the business desk and worked in the Washington bureau. Ornstein is a past president of the Association of Health Care Journalists and an adjunct journalism professor at Columbia University. Follow him on Twitter at @CharlesOrnstein.
Elizabeth Conley is an award-winning photojournalist who moved to Houston from Michigan in September 2016. A professional photojournalist for over 20 years, she still feels she has the best job in the world every time people let her share their stories. Not only was she part of the Chronicle staff covering Super Bowl, Harvey and the World Series, but she also received a three-week fellowship through the International Women's Media Foundation to cover the Great Lakes Region in Africa. Follow her on Twitter and Instagram, or reach out to her by email at elizabeth.conley@chron.com.
Katie Campbell is a video journalist at ProPublica. Campbell is an Emmy Award and Edward R. Murrow award-winning filmmaker and journalist. Campbell began her career as a reporter at newspapers in Minnesota and Florida. She holds a master's degree in narrative journalism from the University of Oregon and worked as a multimedia journalism professor at the University of Oregon School of Journalism and Communication. Follow her on Instagram at @k80camp.
Jon Shapley is a staff videographer for the Houston Chronicle, and he's interested in meeting people and telling stories. A native Houstonian, he joined the Chronicle in 2015. He previously worked at the NPR affiliate in Austin, as well as monthly magazines in Austin and San Antonio. Follow him on Instagram and Twitter, or reach him by email at jon.shapley@chron.com.
Interactives by Jordan Rubio/Houston Chronicle
Design and audience engagement by Rachael Gleason/ Houston Chronicle
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